Nanoscale Photovoltaic Prosthesis For Inducing Repetitive Action Potential Firing in Nerve Cells

Mapping Auditory Nerve Firing Density Using the Compound Action Potential and High-pass Noise Masking By

A critical barrier to future implementation of regenerative treatments for sensorineural hearing loss is the lack of diagnostic tools that can specify the target(s) within the cochlea and auditory nerve for delivery of therapeutic agents. This study used a gerbil model to test the idea of mapping auditory nerve firing density by tracking the amplitude of high-level compound action potentials (C...

Optimal Spike-Timing Dependent Plasticity for Precise Action Potential Firing

In timing-based neural codes, neurons have to emit action potentials at precise moments in time. We use a supervised learning paradigm to derive a synaptic update rule that optimizes via gradient ascent the likelihood of postsynaptic firing at one or several desired firing times. We find that the optimal strategy of upand downregulating synaptic efficacies can be described by a two-phase learni...

The intramuscular nerve action potential.

SiC protective coating for photovoltaic retinal prosthesis.

OBJECTIVE To evaluate plasma-enhanced, chemically vapor deposited (PECVD) amorphous silicon carbide (α-SiC:H) as a protective coating for retinal prostheses and other implantable devices, and to study their failure mechanisms in vivo. APPROACH Retinal prostheses were implanted in rats sub-retinally for up to 1 year. Degradation of implants was characterized by optical and scanning electron mi...

Compound Nerve Action Potential of Common Peroneal Nerve and Sural Nerve Action Potential in Common Peroneal Neuropathy

To enhance the accuracy for determining the precise localization, the findings of the compound nerve action potentials (CNAPs) of the common peroneal nerve (CPN) were investigated in patients with common peroneal mononeuropathy (CPM) in the knee, and the sural sensory nerve action potentials (SNAPs) were also analyzed. Twenty-five patients with CPM in the knee were retrospectively reviewed. The...